The identification of novel mutations in PLCZ1 responsible for human fertilization failure and a therapeutic intervention by artificial oocyte activation. [electronic resource]
Producer: 20210203Description: 80-87 p. digitalISSN:- 1460-2407
- Adult
- Amino Acid Sequence
- Animals
- Calcium Signaling -- drug effects
- Codon, Nonsense
- Conserved Sequence
- Fertilization -- physiology
- Fertilization in Vitro
- Frameshift Mutation
- Genetic Vectors
- HEK293 Cells
- Humans
- Infertility, Male -- genetics
- Ionomycin -- pharmacology
- Male
- Mammals -- genetics
- Mice
- Mice, Inbred ICR
- Middle Aged
- Mutation, Missense
- Oocytes -- drug effects
- Pedigree
- Phosphoinositide Phospholipase C -- genetics
- Sequence Alignment
- Sequence Homology, Amino Acid
- Sperm Injections, Intracytoplasmic
- Treatment Failure
- Exome Sequencing
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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