Piperlongumine regulates epigenetic modulation and alleviates psoriasis-like skin inflammation via inhibition of hyperproliferation and inflammation. [electronic resource]
Producer: 20210114Description: 21 p. digitalISSN:- 2041-4889
- Animals
- Apoptosis -- drug effects
- Cell Proliferation -- drug effects
- Chemokines -- metabolism
- Dioxolanes -- pharmacology
- Epidermis -- pathology
- Epigenesis, Genetic -- drug effects
- HaCaT Cells
- Histone Deacetylase Inhibitors -- pharmacology
- Histone Deacetylases -- metabolism
- Histones -- metabolism
- Humans
- Imiquimod -- adverse effects
- Inflammation -- drug therapy
- Keratin-17 -- metabolism
- Keratinocytes -- drug effects
- Lipopolysaccharides
- Mice
- Mice, Inbred BALB C
- Models, Biological
- Phosphorylation -- drug effects
- Protein Binding -- drug effects
- Psoriasis -- chemically induced
- RAW 264.7 Cells
- STAT3 Transcription Factor -- metabolism
- Skin -- pathology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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