A dual druggable genome-wide siRNA and compound library screening approach identifies modulators of parkin recruitment to mitochondria. [electronic resource]
Producer: 20201020Description: 3285-3300 p. digitalISSN:- 1083-351X
- Benzazepines -- chemistry
- HeLa Cells
- Humans
- Hydrazones -- chemistry
- Indoles -- chemistry
- Membrane Potential, Mitochondrial -- drug effects
- Mitochondria -- metabolism
- Mitophagy -- drug effects
- Principal Component Analysis
- Protein Kinases -- chemistry
- RNA Interference
- RNA, Small Interfering -- metabolism
- Small Molecule Libraries -- chemistry
- Ubiquitin-Conjugating Enzymes -- antagonists & inhibitors
- Ubiquitin-Protein Ligases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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