Testosterone inhibits cAMP-induced de Novo synthesis of Leydig cell cytochrome P-450(17 alpha) by an androgen receptor-mediated mechanism. [electronic resource]
Producer: 19870917Description: 11200-6 p. digitalISSN:- 0021-9258
- 8-Bromo Cyclic Adenosine Monophosphate -- pharmacology
- Aminoglutethimide -- pharmacology
- Animals
- Cells, Cultured
- Cyclic AMP -- pharmacology
- Cytochrome P-450 Enzyme Inhibitors
- Cytochrome P-450 Enzyme System -- biosynthesis
- Dexamethasone -- pharmacology
- Enzyme Induction -- drug effects
- Estradiol -- pharmacology
- Leydig Cells -- drug effects
- Male
- Mice
- Nandrolone -- analogs & derivatives
- Receptors, Androgen -- drug effects
- Steroid 17-alpha-Hydroxylase -- antagonists & inhibitors
- Steroid Hydroxylases -- biosynthesis
- Testosterone -- biosynthesis
- Tetrahydronaphthalenes -- pharmacology
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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