Curcumin has immunomodulatory effects on RANKL-stimulated osteoclastogenesis in vitro and titanium nanoparticle-induced bone loss in vivo. [electronic resource]
Producer: 20210423Description: 1553-1567 p. digitalISSN:- 1582-4934
- Actins -- metabolism
- Animals
- Bone Resorption -- chemically induced
- Cell Death -- drug effects
- Cell Differentiation -- drug effects
- Cell Polarity -- drug effects
- Curcumin -- chemistry
- Cytokines -- metabolism
- Immunomodulation -- drug effects
- Macrophages -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Models, Biological
- NF-kappa B -- metabolism
- Nanoparticles -- toxicity
- Osteoclasts -- drug effects
- Osteogenesis -- drug effects
- Osteolysis -- complications
- Phosphorylation -- drug effects
- Protective Agents -- pharmacology
- Proto-Oncogene Proteins c-akt -- metabolism
- RANK Ligand -- pharmacology
- RAW 264.7 Cells
- Signal Transduction -- drug effects
- Titanium -- toxicity
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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