Activity of M3814, an Oral DNA-PK Inhibitor, In Combination with Topoisomerase II Inhibitors in Ovarian Cancer Models. [electronic resource]
Producer: 20201106Description: 18882 p. digitalISSN:- 2045-2322
- Animals
- Antineoplastic Agents -- pharmacology
- Carcinoma, Ovarian Epithelial -- drug therapy
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- DNA Damage -- drug effects
- DNA-Activated Protein Kinase -- antagonists & inhibitors
- Doxorubicin -- analogs & derivatives
- Drug Therapy, Combination
- Etoposide -- pharmacology
- Female
- Humans
- Mice
- Mice, Nude
- Ovarian Neoplasms -- drug therapy
- Polyethylene Glycols -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- Topoisomerase II Inhibitors -- pharmacology
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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