Inhibition of tyrosine kinase signaling by tyrphostin AG126 downregulates the IL-21/IL-21R and JAK/STAT pathway in the BTBR mouse model of autism. [electronic resource]
Producer: 20210122Description: 1-11 p. digitalISSN:- 1872-9711
- Animals
- Autism Spectrum Disorder -- metabolism
- Disease Models, Animal
- Down-Regulation
- Enzyme Inhibitors -- administration & dosage
- Interleukin-21 Receptor alpha Subunit -- metabolism
- Interleukins -- metabolism
- Janus Kinases -- metabolism
- Male
- Mice, Inbred C57BL
- Mice, Transgenic
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Tyrphostins -- administration & dosage
- Interleukin-21
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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