Formation of SUMO3-conjugated chains of MAVS induced by poly(dA:dT), a ligand of RIG-I, enhances the aggregation of MAVS that drives the secretion of interferon-β in human keratinocytes. [electronic resource]
Producer: 20200831Description: 939-944 p. digitalISSN:- 1090-2104
- Adaptor Proteins, Signal Transducing -- metabolism
- Cell Line
- DEAD Box Protein 58 -- metabolism
- Humans
- Interferon-beta -- metabolism
- Keratinocytes -- drug effects
- Ligands
- Poly dA-dT -- pharmacology
- Protein Aggregates -- drug effects
- Protein Domains
- RNA, Small Interfering -- metabolism
- Receptors, Immunologic
- Salicylates -- pharmacology
- Sequence Deletion
- Sumoylation -- drug effects
- Ubiquitin-Conjugating Enzymes -- metabolism
- Ubiquitins -- metabolism
- Ubiquitin-Conjugating Enzyme UBC9
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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