A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells. [electronic resource]
Producer: 20200310Description: 5444 p. digitalISSN:- 2041-1723
- A549 Cells
- Carcinoma, Non-Small-Cell Lung -- metabolism
- Cell Line, Tumor
- Class I Phosphatidylinositol 3-Kinases -- drug effects
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- Glucose -- metabolism
- Glucose Transporter Type 1 -- drug effects
- High-Throughput Screening Assays
- Humans
- Lung Neoplasms -- metabolism
- Phenylenediamines -- pharmacology
- Phosphorylation
- Protein Kinase Inhibitors -- pharmacology
- Pyrazoles -- pharmacology
- Pyrimidines -- pharmacology
- Quinazolines -- pharmacology
- RNA Polymerase II -- drug effects
- RNA, Messenger -- metabolism
- Signal Transduction
- Triazines -- pharmacology
- Cyclin-Dependent Kinase-Activating Kinase
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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