CDK4/CDK6 inhibition as a novel strategy to suppress the growth and survival of BCR-ABL1 [electronic resource]
Producer: 20200430Description: 111-121 p. digitalISSN:- 2352-3964
- Adult
- Aged
- Apoptosis -- drug effects
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cyclin-Dependent Kinase 4 -- antagonists & inhibitors
- Cyclin-Dependent Kinase 6 -- antagonists & inhibitors
- Dose-Response Relationship, Drug
- Drug Resistance, Neoplasm -- genetics
- Drug Synergism
- Female
- Fusion Proteins, bcr-abl -- genetics
- Humans
- Hydroxyurea -- pharmacology
- Imidazoles -- pharmacology
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive -- genetics
- Male
- Middle Aged
- Mutation
- Protein Kinase Inhibitors -- pharmacology
- Pyridazines -- pharmacology
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Publication Type: Journal Article
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