FGF23 induced left ventricular hypertrophy mediated by FGFR4 signaling in the myocardium is attenuated by soluble Klotho in mice. [electronic resource]
Producer: 20210121Description: 66-74 p. digitalISSN:- 1095-8584
- Animals
- Cytoprotection
- Fibroblast Growth Factor-23
- Fibroblast Growth Factors -- metabolism
- Gene Deletion
- Glucuronidase -- metabolism
- HEK293 Cells
- Humans
- Hypertrophy, Left Ventricular -- diagnostic imaging
- Kidney Tubules, Distal -- pathology
- Klotho Proteins
- Mice, Inbred C57BL
- Myocardium -- metabolism
- Myocytes, Cardiac -- metabolism
- Receptor, Fibroblast Growth Factor, Type 1 -- metabolism
- Receptor, Fibroblast Growth Factor, Type 4 -- metabolism
- Signal Transduction
- Solubility
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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