Impaired inflammasome activation and bacterial clearance in G6PD deficiency due to defective NOX/p38 MAPK/AP-1 redox signaling. [electronic resource]
Producer: 20200930Description: 101363 p. digitalISSN:- 2213-2317
- Adult
- Aged
- Case-Control Studies
- Down-Regulation
- Female
- Gene Knockdown Techniques
- Glucosephosphate Dehydrogenase Deficiency -- genetics
- HEK293 Cells
- Humans
- Interleukin-1beta -- genetics
- Leukocytes, Mononuclear -- cytology
- Lipopolysaccharides -- adverse effects
- Male
- NADPH Oxidases -- metabolism
- THP-1 Cells -- drug effects
- Transcription Factor AP-1 -- metabolism
- Young Adult
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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