eIF4A inhibition circumvents uncontrolled DNA replication mediated by 4E-BP1 loss in pancreatic cancer. [electronic resource]
Producer: 20201027ISSN:- 2379-3708
- Adaptor Proteins, Signal Transducing -- genetics
- Animals
- Carcinoma, Pancreatic Ductal -- genetics
- Cell Cycle Proteins -- genetics
- Cell Line, Tumor
- DNA Replication
- Eukaryotic Initiation Factor-4A -- antagonists & inhibitors
- Humans
- Mice
- Pancreatic Neoplasms -- genetics
- Protein Biosynthesis
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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