DNA methyltransferase inhibitors induce a BRCAness phenotype that sensitizes NSCLC to PARP inhibitor and ionizing radiation. [electronic resource]
Producer: 20200407Description: 22609-22618 p. digitalISSN:- 1091-6490
- Animals
- Antineoplastic Agents
- BRCA1 Protein -- genetics
- BRCA2 Protein -- genetics
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Cell Line, Tumor
- Combined Modality Therapy
- DNA Modification Methylases -- antagonists & inhibitors
- DNA Repair -- drug effects
- Drug Therapy, Combination
- Enzyme Inhibitors -- administration & dosage
- Female
- Homologous Recombination -- drug effects
- Humans
- Lung Neoplasms -- drug therapy
- Male
- Mice
- Phthalazines -- administration & dosage
- Poly(ADP-ribose) Polymerase Inhibitors -- administration & dosage
- Radiation, Ionizing
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.