Design and Evaluation of PEGylated Liposomal Formulation of a Novel Multikinase Inhibitor for Enhanced Chemosensitivity and Inhibition of Metastatic Pancreatic Ductal Adenocarcinoma. [electronic resource]
Producer: 20200904Description: 2703-2713 p. digitalISSN:- 1520-4812
- Adenocarcinoma -- pathology
- Animals
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Deoxycytidine -- analogs & derivatives
- Drug Compounding
- Drug Design
- ErbB Receptors -- metabolism
- Female
- Humans
- Liposomes -- chemistry
- Mice
- Neoplasm Metastasis
- Pancreatic Neoplasms -- pathology
- Polyethylene Glycols -- chemistry
- Protein Kinase Inhibitors -- chemistry
- Proteolysis -- drug effects
- Xenograft Model Antitumor Assays
- Gemcitabine
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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