Optimized CRISPR guide RNA design for two high-fidelity Cas9 variants by deep learning. [electronic resource]
Producer: 20200106Description: 4284 p. digitalISSN:- 2041-1723
- Animals
- Base Sequence -- genetics
- CRISPR-Cas Systems -- genetics
- Cell Line, Tumor
- Clustered Regularly Interspaced Short Palindromic Repeats -- genetics
- Deep Learning
- Endonucleases -- metabolism
- Gene Editing -- methods
- HEK293 Cells
- HeLa Cells
- Humans
- INDEL Mutation -- genetics
- Internet
- Mice
- Promoter Regions, Genetic -- genetics
- RNA, Guide, CRISPR-Cas Systems -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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