Carboxyamidotriazole combined with IDO1-Kyn-AhR pathway inhibitors profoundly enhances cancer immunotherapy. [electronic resource]
Producer: 20200813Description: 246 p. digitalISSN:- 2051-1426
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis
- CD8-Positive T-Lymphocytes -- drug effects
- Cell Proliferation
- Drug Therapy, Combination
- Flavones -- pharmacology
- Humans
- Immunotherapy
- Indoleamine-Pyrrole 2,3,-Dioxygenase -- antagonists & inhibitors
- Kynurenine -- metabolism
- Lymphocyte Activation -- immunology
- Melanoma -- drug therapy
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Transgenic
- Receptors, Aryl Hydrocarbon -- antagonists & inhibitors
- Triazoles -- pharmacology
- Tryptophan -- pharmacology
- Tumor Cells, Cultured
- Tumor Microenvironment -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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