Inhibition of anti-viral responses in intestinal epithelial cells by epigenetic modifying drugs is mediated by a reduction in viral pattern recognition receptor expression and activity. [electronic resource]
Producer: 20200207Description: 527-537 p. digitalISSN:- 1532-2513
- Antiviral Agents -- pharmacology
- DNA (Cytosine-5-)-Methyltransferases -- antagonists & inhibitors
- DNA Methylation -- drug effects
- Decitabine -- pharmacology
- Epigenesis, Genetic -- drug effects
- Epithelial Cells -- drug effects
- Gene Knockdown Techniques
- HCT116 Cells
- Histone Deacetylase Inhibitors -- pharmacology
- Histone Deacetylases -- metabolism
- Humans
- Hydroxamic Acids -- pharmacology
- Immunity, Innate -- drug effects
- Intestinal Mucosa -- drug effects
- Poly I-C -- pharmacology
- Repressor Proteins -- antagonists & inhibitors
- Toll-Like Receptor 3 -- genetics
- DNA Methyltransferase 3B
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Publication Type: Journal Article
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