Isoliquiritigenin, an Orally Available Natural FLT3 Inhibitor from Licorice, Exhibits Selective Anti-Acute Myeloid Leukemia Efficacy In Vitro and In Vivo. [electronic resource]
Producer: 20200303Description: 589-599 p. digitalISSN:- 1521-0111
- Administration, Oral
- Animals
- Cell Line, Tumor
- Cell Survival -- drug effects
- Chalcones -- administration & dosage
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- administration & dosage
- Female
- Glycyrrhiza
- Humans
- Leukemia, Myeloid, Acute -- drug therapy
- Mice
- Mice, Inbred NOD
- Mice, SCID
- Molecular Docking Simulation -- methods
- Treatment Outcome
- Xenograft Model Antitumor Assays -- methods
- fms-Like Tyrosine Kinase 3 -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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