Exhaustion of CD4+ T-cells mediated by the Kynurenine Pathway in Melanoma. [electronic resource]
Producer: 20201022Description: 12150 p. digitalISSN:- 2045-2322
- B7-H1 Antigen -- genetics
- CD4-Positive T-Lymphocytes -- cytology
- Cell Line
- Cell Proliferation -- drug effects
- Coculture Techniques
- Culture Media, Conditioned -- pharmacology
- Forkhead Transcription Factors -- genetics
- Gene Expression Regulation
- Humans
- Indoleamine-Pyrrole 2,3,-Dioxygenase -- metabolism
- Interferon-gamma -- pharmacology
- Kynurenic Acid -- analysis
- Kynurenine -- metabolism
- Melanoma -- immunology
- Metabolic Networks and Pathways
- Metabolomics
- Proto-Oncogene Proteins B-raf -- genetics
- Skin Neoplasms -- immunology
- Tryptophan -- analysis
- Tumor Microenvironment
- Up-Regulation
- Melanoma, Cutaneous Malignant
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Publication Type: Journal Article
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