TLX3 repressed SNAI1-induced epithelial-mesenchymal transition by directly constraining STAT3 phosphorylation and functionally sensitized 5-FU chemotherapy in hepatocellular carcinoma. [electronic resource]
Producer: 20200406Description: 1696-1711 p. digitalISSN:- 1449-2288
- Animals
- Apoptosis -- drug effects
- Carcinoma, Hepatocellular -- drug therapy
- Cell Line, Tumor
- Chromatin Immunoprecipitation
- Epithelial-Mesenchymal Transition -- drug effects
- Fluorouracil -- therapeutic use
- HeLa Cells
- Homeodomain Proteins -- genetics
- Humans
- Immunoblotting
- Immunoprecipitation
- Liver Neoplasms -- drug therapy
- Male
- Mice
- Mice, Nude
- Phosphorylation -- drug effects
- Proteomics -- methods
- RNA Interference
- STAT3 Transcription Factor -- genetics
- Wound Healing -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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