Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells. [electronic resource]
Producer: 20200423Description: 338-351 p. digitalISSN:- 2213-6711
- AMP-Activated Protein Kinases -- metabolism
- Bone Morphogenetic Protein 4 -- pharmacology
- Cell Differentiation -- drug effects
- Cell Lineage
- Citric Acid Cycle -- drug effects
- Endoderm -- cytology
- Homeodomain Proteins -- genetics
- Human Embryonic Stem Cells -- cytology
- Humans
- Mesoderm -- cytology
- Mitochondria -- drug effects
- Oxidative Phosphorylation -- drug effects
- Pyruvic Acid -- pharmacology
- Signal Transduction -- drug effects
- T-Box Domain Proteins -- genetics
- TOR Serine-Threonine Kinases -- metabolism
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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