A kinome-wide shRNA screen uncovers vaccinia-related kinase 3 (VRK3) as an essential gene for diffuse intrinsic pontine glioma survival. [electronic resource]
Producer: 20200129Description: 6479-6490 p. digitalISSN:- 1476-5594
- Brain Stem Neoplasms -- diagnosis
- Cell Survival -- genetics
- Cells, Cultured
- Diffuse Intrinsic Pontine Glioma -- diagnosis
- Genes, Essential
- HEK293 Cells
- Humans
- Phosphatidylinositol 3-Kinases -- analysis
- Phosphotransferases -- analysis
- Prognosis
- Protein Serine-Threonine Kinases -- analysis
- RNA, Small Interfering -- analysis
- Sequence Analysis, RNA -- methods
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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