Evaluation of neuroprotective activity of digoxin and semisynthetic derivatives against partial chemical ischemia. [electronic resource]
Producer: 20200914Description: 17108-17122 p. digitalISSN:- 1097-4644
- Animals
- Brain Ischemia -- prevention & control
- Caco-2 Cells
- Cell Hypoxia -- drug effects
- Cell Line, Tumor
- Cell Survival -- drug effects
- Cholesterol -- metabolism
- Digoxin -- analogs & derivatives
- Gene Expression -- drug effects
- Glutathione -- metabolism
- Glutathione Peroxidase -- genetics
- Humans
- Lipid Peroxidation -- drug effects
- Mice
- Models, Biological
- Neurons -- drug effects
- Neuroprotective Agents -- chemical synthesis
- Oxidative Stress -- drug effects
- Phospholipids -- metabolism
- Reactive Oxygen Species -- antagonists & inhibitors
- Sodium Azide -- antagonists & inhibitors
- Sodium-Potassium-Exchanging ATPase -- genetics
- Superoxide Dismutase -- genetics
- Thiobarbituric Acid Reactive Substances -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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