Cyp3a11 metabolism-based chronotoxicity of brucine in mice. [electronic resource]
Producer: 20190729Description: 188-195 p. digitalISSN:- 1879-3169
- Alanine Transaminase -- blood
- Animals
- Aspartate Aminotransferases -- blood
- Basic Helix-Loop-Helix Transcription Factors -- deficiency
- Chemical and Drug Induced Liver Injury -- blood
- Circadian Rhythm -- genetics
- Cytochrome P-450 CYP3A -- metabolism
- Drug Chronotherapy
- HEK293 Cells
- Humans
- Liver -- drug effects
- Male
- Membrane Proteins -- metabolism
- Mice, Inbred C57BL
- Mice, Knockout
- Microsomes, Liver -- drug effects
- Nerve Tissue Proteins -- deficiency
- Photoperiod
- Strychnine -- administration & dosage
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Publication Type: Comparative Study; Journal Article
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