Effects of metformin and phenformin on apoptosis and epithelial-mesenchymal transition in chemoresistant rectal cancer. [electronic resource]
Producer: 20190930Description: 2834-2845 p. digitalISSN:- 1349-7006
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Chemoradiotherapy -- methods
- Colon -- pathology
- Colonic Neoplasms -- pathology
- Drug Resistance, Neoplasm -- drug effects
- Epithelial-Mesenchymal Transition -- drug effects
- Fluorouracil -- pharmacology
- Humans
- Male
- Metformin -- pharmacology
- Mice
- Mice, Nude
- Neoplasm Recurrence, Local
- Phenformin -- pharmacology
- Rectal Neoplasms -- pathology
- STAT3 Transcription Factor -- metabolism
- Signal Transduction -- drug effects
- Smad Proteins -- metabolism
- Transforming Growth Factor beta -- metabolism
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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