Design, synthesis and antitumor study of a series of N-Cyclic sulfamoylaminoethyl substituted 1,2,5-oxadiazol-3-amines as new indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitors. [electronic resource]
Producer: 20191104Description: 38-55 p. digitalISSN:- 1768-3254
- Amines -- chemical synthesis
- Animals
- Antineoplastic Agents -- chemical synthesis
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Drug Design
- Drug Screening Assays, Antitumor
- Enzyme Inhibitors -- chemical synthesis
- Female
- HEK293 Cells
- Humans
- Indoleamine-Pyrrole 2,3,-Dioxygenase -- antagonists & inhibitors
- Male
- Mice
- Mice, Inbred BALB C
- Molecular Structure
- Oxadiazoles -- chemical synthesis
- Rats
- Rats, Sprague-Dawley
- Structure-Activity Relationship
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Publication Type: Journal Article
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