Durable Response of Enzalutamide-resistant Prostate Cancer to Supraphysiological Testosterone Is Associated with a Multifaceted Growth Suppression and Impaired DNA Damage Response Transcriptomic Program in Patient-derived Xenografts. [electronic resource]
Producer: 20210318Description: 144-155 p. digitalISSN:- 1873-7560
- Animals
- Benzamides
- DNA Repair
- Drug Resistance, Neoplasm
- Humans
- Male
- Mice
- Mice, Inbred C57BL
- Nitriles
- Phenylthiohydantoin -- analogs & derivatives
- Prostatic Neoplasms, Castration-Resistant -- drug therapy
- Testosterone -- administration & dosage
- Time Factors
- Transcriptome
- Treatment Failure
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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