14-3-3ζ targeting induced senescence in Hep-2 laryngeal cancer cell through deneddylation of Cullin1 in the Skp1-Cullin-F-box protein complex. [electronic resource]
Producer: 20191025Description: e12654 p. digitalISSN:- 1365-2184
- 14-3-3 Proteins -- antagonists & inhibitors
- Animals
- COP9 Signalosome Complex -- antagonists & inhibitors
- Cell Cycle Checkpoints
- Cell Line, Tumor
- Cell Proliferation
- Cellular Senescence
- Cullin Proteins -- metabolism
- Cyclin-Dependent Kinase Inhibitor p27 -- genetics
- F-Box Proteins -- metabolism
- Humans
- Intracellular Signaling Peptides and Proteins -- antagonists & inhibitors
- Laryngeal Neoplasms -- metabolism
- Male
- Mice
- Mice, Nude
- Peptide Hydrolases -- genetics
- RNA Interference
- RNA, Small Interfering -- metabolism
- S-Phase Kinase-Associated Proteins -- genetics
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Publication Type: Journal Article
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