Two open-label, single arm, non-randomized phase II studies of irinotecan for the treatment of metastatic breast cancer in patients with increased copy number of the topoisomerase I gene. [electronic resource]
Producer: 20191223Description: 573 p. digitalISSN:- 1471-2407
- Aged
- Antineoplastic Agents -- therapeutic use
- Biomarkers, Pharmacological
- Breast Neoplasms -- diagnosis
- DNA Topoisomerases, Type I -- genetics
- Drug Therapy, Combination
- Female
- Gene Dosage
- Humans
- Irinotecan -- therapeutic use
- Middle Aged
- Predictive Value of Tests
- Prognosis
- Receptor, ErbB-2 -- metabolism
- Topoisomerase I Inhibitors -- therapeutic use
- Trastuzumab -- therapeutic use
- Treatment Outcome
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Publication Type: Clinical Trial, Phase II; Journal Article
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