Elevated VMP1 expression in acute myeloid leukemia amplifies autophagy and is protective against venetoclax-induced apoptosis. [electronic resource]
Producer: 20200625Description: 421 p. digitalISSN:- 2041-4889
- Animals
- Antigens, CD34 -- metabolism
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Autophagy
- Bridged Bicyclo Compounds, Heterocyclic -- pharmacology
- Cell Cycle Checkpoints
- Female
- Fetal Blood -- cytology
- Humans
- Leukemia, Myeloid, Acute -- metabolism
- Leukocytes, Mononuclear -- cytology
- Membrane Proteins -- antagonists & inhibitors
- Mice
- Mice, Transgenic
- Mitochondria -- metabolism
- Mitochondrial Turnover -- drug effects
- RNA Interference
- RNA, Small Interfering -- metabolism
- Sequestosome-1 Protein -- metabolism
- Sulfonamides -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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