Suppression of B cell function by methotrexate and trimetrexate. Evidence for inhibition of purine biosynthesis as a major mechanism of action. [electronic resource]
Producer: 19880803Description: 410-6 p. digitalISSN:- 0022-1767
- Animals
- Antibody Formation -- drug effects
- B-Lymphocytes -- drug effects
- Cell Differentiation -- drug effects
- Female
- Folic Acid Antagonists -- pharmacology
- Immunoglobulins -- biosynthesis
- Immunosuppressive Agents -- pharmacology
- Kinetics
- Lymphocyte Activation -- drug effects
- Methotrexate -- pharmacology
- Mice
- Purines -- antagonists & inhibitors
- Quinazolines -- pharmacology
- Trimetrexate
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Publication Type: Journal Article
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