Degradable antimicrobial polycarbonates with unexpected activity and selectivity for treating multidrug-resistant Klebsiella pneumoniae lung infection in mice. [electronic resource]
Producer: 20200811Description: 268-280 p. digitalISSN:- 1878-7568
- Animals
- Anti-Bacterial Agents -- pharmacology
- Anti-Infective Agents -- pharmacology
- Biocompatible Materials
- Cell Line
- Cell Membrane -- metabolism
- Cytosol -- metabolism
- Drug Resistance, Multiple, Bacterial
- Epithelial Cells -- drug effects
- Female
- Guanidine -- pharmacology
- Humans
- Imipenem -- pharmacology
- Kinetics
- Klebsiella Infections -- drug therapy
- Klebsiella pneumoniae
- Lung Diseases -- drug therapy
- Mice
- Mice, Inbred BALB C
- Mice, Inbred ICR
- Microbial Sensitivity Tests
- Pneumonia, Bacterial -- drug therapy
- Polycarboxylate Cement -- pharmacology
- Polymers -- chemistry
- Protein Binding
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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