Doxorubicin-induced cardiotoxicity is maturation dependent due to the shift from topoisomerase IIα to IIβ in human stem cell derived cardiomyocytes. [electronic resource]
Producer: 20200806Description: 4627-4639 p. digitalISSN:- 1582-4934
- Cardiotoxicity -- enzymology
- Cell Death -- drug effects
- Cell Differentiation
- Cells, Cultured
- DNA Damage
- DNA Topoisomerases, Type II -- metabolism
- Doxorubicin -- adverse effects
- Humans
- Induced Pluripotent Stem Cells -- cytology
- Models, Biological
- Myocytes, Cardiac -- enzymology
- Poly-ADP-Ribose Binding Proteins -- metabolism
- Reactive Oxygen Species -- metabolism
- Time Factors
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.