Genetic knockout of myosin light chain kinase (MLCK210) prevents cerebral microhemorrhages and attenuates neuroinflammation in a mouse model of vascular cognitive impairment and dementia. [electronic resource]
Producer: 20200521Description: 671-679 p. digitalISSN:- 2509-2723
- Animals
- Cerebral Hemorrhage -- pathology
- Cognitive Dysfunction -- metabolism
- Dementia -- metabolism
- Disease Models, Animal
- Hyperhomocysteinemia
- Interleukin-10 -- genetics
- Interleukin-1beta -- genetics
- Interleukin-6 -- metabolism
- Lectins -- genetics
- Mice, Knockout
- Myosin-Light-Chain Kinase -- genetics
- RNA, Messenger -- metabolism
- Receptors, Interleukin-1 -- genetics
- Tumor Necrosis Factor-alpha -- genetics
- Up-Regulation
- beta-N-Acetylhexosaminidases -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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