A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatric AML. [electronic resource]
Producer: 20190607Description: 2189 p. digitalISSN:- 2041-1723
- Adult
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Bone Marrow -- pathology
- Bone Marrow Transplantation
- Cell Line, Tumor
- Child
- Child, Preschool
- Cytarabine -- pharmacology
- Deoxycytidine -- analogs & derivatives
- Disease-Free Survival
- Female
- High-Throughput Screening Assays -- methods
- Humans
- Infant
- Janus Kinase Inhibitors -- pharmacology
- Leukemia, Experimental -- drug therapy
- Leukemia, Myeloid, Acute -- drug therapy
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Taxoids -- pharmacology
- Whole-Body Irradiation -- adverse effects
- Xenograft Model Antitumor Assays
- Young Adult
- Gemcitabine
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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