The ginsenoside Rk3 exerts anti-esophageal cancer activity in vitro and in vivo by mediating apoptosis and autophagy through regulation of the PI3K/Akt/mTOR pathway. [electronic resource]
Producer: 20200124Description: e0216759 p. digitalISSN:- 1932-6203
- Animals
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- drug effects
- Autophagy -- drug effects
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Esophageal Neoplasms -- drug therapy
- Female
- Ginsenosides -- pharmacology
- Humans
- In Vitro Techniques
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Models, Biological
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction -- drug effects
- TOR Serine-Threonine Kinases -- metabolism
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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