A Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1. [electronic resource]
Producer: 20200824Description: 962-979 p. digitalISSN:- 2159-8290
- Animals
- Cell Line, Tumor
- Cell Plasticity -- genetics
- Forkhead Transcription Factors -- genetics
- Gain of Function Mutation
- Gene Expression Profiling
- Humans
- Leukemia, Myeloid, Acute -- genetics
- Mice
- Mice, Inbred NOD
- Mice, Knockout
- Mice, SCID
- Mice, Transgenic
- Neoplastic Stem Cells -- metabolism
- Pluripotent Stem Cells -- metabolism
- Tumor Suppressor Protein p53 -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: News; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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