Myeloid translocation gene CBFA2T3 directs a relapse gene program and determines patient-specific outcomes in AML. [electronic resource]
Producer: 20200511Description: 1379-1393 p. digitalISSN:- 2473-9537
- Animals
- Core Binding Factor Alpha 2 Subunit -- antagonists & inhibitors
- Cyclin-Dependent Kinase Inhibitor p21 -- genetics
- Disease-Free Survival
- G1 Phase Cell Cycle Checkpoints
- Humans
- Kaplan-Meier Estimate
- Leukemia, Myeloid, Acute -- genetics
- Mice
- Mice, Knockout
- Oncogene Proteins, Fusion -- antagonists & inhibitors
- Prognosis
- RNA Interference
- RNA, Small Interfering -- metabolism
- RUNX1 Translocation Partner 1 Protein -- antagonists & inhibitors
- Recurrence
- Repressor Proteins -- antagonists & inhibitors
- Translocation, Genetic
- Tumor Cells, Cultured
- p300-CBP Transcription Factors -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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