Design and synthesis of novel 2,4-disubstituted aminopyrimidines: reversible non-covalent T790M EGFR inhibitors. [electronic resource]
Producer: 20190904Description: 393-412 p. digitalISSN:- 1532-4281
- Acrylamides -- adverse effects
- Aniline Compounds -- adverse effects
- Carcinoma, Non-Small-Cell Lung -- complications
- Cardiotoxicity -- etiology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Drug Screening Assays, Antitumor
- ErbB Receptors -- antagonists & inhibitors
- Humans
- Molecular Docking Simulation
- Protein Kinase Inhibitors -- chemical synthesis
- Pyrimidines -- chemical synthesis
- Structure-Activity Relationship
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Publication Type: Journal Article
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