2-Hydroxy-3-methylanthraquinone inhibits lung carcinoma cells through modulation of IL-6-induced JAK2/STAT3 pathway. [electronic resource]
Producer: 20200107Description: 152848 p. digitalISSN:- 1618-095X
- A549 Cells
- Animals
- Anthraquinones -- pharmacology
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- drug effects
- Carcinoma, Lewis Lung -- drug therapy
- Cytokines -- metabolism
- Down-Regulation -- drug effects
- Drugs, Chinese Herbal -- pharmacology
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Interleukin-6 -- metabolism
- Janus Kinase 2 -- metabolism
- Lung Neoplasms -- drug therapy
- Metalloendopeptidases -- genetics
- Mice
- Phosphorylation -- drug effects
- STAT3 Transcription Factor -- metabolism
- Signal Transduction -- drug effects
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Publication Type: Journal Article
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