Curcumin induces apoptosis in JAK2-mutated cells by the inhibition of JAK2/STAT and mTORC1 pathways. [electronic resource]
Producer: 20200729Description: 4349-4357 p. digitalISSN:- 1582-4934
- Adult
- Aged
- Aged, 80 and over
- Antineoplastic Agents -- pharmacology
- Apoptosis
- Biomarkers, Tumor
- Case-Control Studies
- Cell Movement
- Cell Proliferation
- Curcumin -- pharmacology
- Female
- Follow-Up Studies
- Gene Expression Regulation, Neoplastic
- Humans
- Janus Kinase 2 -- antagonists & inhibitors
- Leukemia, Erythroblastic, Acute -- drug therapy
- Leukocytes, Mononuclear -- drug effects
- Male
- Mechanistic Target of Rapamycin Complex 1 -- antagonists & inhibitors
- Middle Aged
- Mutation
- Myeloproliferative Disorders -- drug therapy
- Phosphorylation
- STAT Transcription Factors -- antagonists & inhibitors
- Signal Transduction
- Tumor Cells, Cultured
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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