DAXX, as a Tumor Suppressor, Impacts DNA Damage Repair and Sensitizes BRCA-Proficient TNBC Cells to PARP Inhibitors. [electronic resource]
Producer: 20191125Description: 533-544 p. digitalISSN:- 1476-5586
- Adaptor Proteins, Signal Transducing -- antagonists & inhibitors
- Animals
- Benzimidazoles -- pharmacology
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Co-Repressor Proteins
- DNA Damage -- drug effects
- DNA Repair -- drug effects
- Female
- Heterografts
- Humans
- Mice
- Molecular Chaperones
- Morpholines -- pharmacology
- Nuclear Proteins -- antagonists & inhibitors
- Poly (ADP-Ribose) Polymerase-1 -- genetics
- Poly(ADP-ribose) Polymerase Inhibitors -- pharmacology
- Promoter Regions, Genetic -- drug effects
- Pyrroles -- pharmacology
- Rad51 Recombinase -- genetics
- Triple Negative Breast Neoplasms -- drug therapy
- Tumor Suppressor Proteins -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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