CRISPR-Cas9-Mediated Correction of the G189R-PAX2 Mutation in Induced Pluripotent Stem Cells from a Patient with Focal Segmental Glomerulosclerosis. [electronic resource]
Producer: 20200302Description: 108-120 p. digitalISSN:- 2573-1602
- Adult
- CRISPR-Associated Protein 9 -- genetics
- CRISPR-Cas Systems -- genetics
- Cell Differentiation
- Clustered Regularly Interspaced Short Palindromic Repeats -- genetics
- Genetic Engineering -- methods
- Germ-Line Mutation -- genetics
- Glomerulosclerosis, Focal Segmental -- genetics
- Humans
- Induced Pluripotent Stem Cells -- metabolism
- Kidney Glomerulus -- metabolism
- Mutation -- genetics
- PAX2 Transcription Factor -- analysis
- Podocytes -- chemistry
- Polymorphism, Single Nucleotide -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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