An experimentally validated approach to calculate the blood-brain barrier permeability of small molecules. [electronic resource]
Producer: 20201014Description: 6117 p. digitalISSN:- 2045-2322
- Blood-Brain Barrier -- cytology
- Central Nervous System Agents -- pharmacokinetics
- Chemistry, Pharmaceutical -- methods
- Diffusion
- Drug Development -- methods
- Endothelial Cells
- Endothelium, Vascular -- cytology
- Hot Temperature
- Humans
- Kinetics
- Microvessels -- cytology
- Models, Cardiovascular
- Models, Chemical
- Molecular Dynamics Simulation
- Permeability
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Validation Study
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