Aloin Reduces HMGB1-Mediated Septic Responses and Improves Survival in Septic Mice by Activation of the SIRT1 and PI3K/Nrf2/HO-1 Signaling Axis. [electronic resource]
Producer: 20191017Description: 613-633 p. digitalISSN:- 1793-6853
- Aloe -- chemistry
- Animals
- Disease Models, Animal
- Emodin -- administration & dosage
- HMGB1 Protein -- antagonists & inhibitors
- Heme Oxygenase-1 -- metabolism
- Human Umbilical Vein Endothelial Cells -- metabolism
- Humans
- Male
- Mice, Inbred C57BL
- NF-E2-Related Factor 2 -- metabolism
- Phosphatidylinositol 3-Kinases -- metabolism
- Phytotherapy
- Sepsis -- drug therapy
- Signal Transduction -- drug effects
- Sirtuin 1 -- metabolism
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Publication Type: Journal Article
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