E3 ubiquitin ligase tripartite motif 7 positively regulates the TLR4-mediated immune response via its E3 ligase domain in macrophages. [electronic resource]
Producer: 20190506Description: 126-133 p. digitalISSN:- 1872-9142
- Animals
- Antigen-Presenting Cells -- drug effects
- Carrier Proteins -- chemistry
- Cytokines -- metabolism
- Down-Regulation -- drug effects
- Gene Silencing -- drug effects
- Immunity -- drug effects
- Inflammation Mediators -- metabolism
- Interferon Type I -- metabolism
- Lipopolysaccharides
- Macrophages -- drug effects
- Mice, Inbred C57BL
- Oligodeoxyribonucleotides -- pharmacology
- Protein Domains
- Signal Transduction -- drug effects
- Toll-Like Receptor 4 -- metabolism
- Tripartite Motif Proteins
- Ubiquitin-Protein Ligases
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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