Selected nitrostyrene compounds demonstrate potent activity in chronic lymphocytic leukaemia cells, including those with poor prognostic markers. [electronic resource]
Producer: 20190624Description: 3127-3136 p. digitalISSN:- 1791-2431
- Aged
- Antineoplastic Combined Chemotherapy Protocols -- chemistry
- Apoptosis -- drug effects
- Biomarkers, Tumor -- genetics
- Cell Line, Tumor
- Cell Survival -- drug effects
- Drug Screening Assays, Antitumor
- Drug Synergism
- Female
- Humans
- Inhibitory Concentration 50
- Leukemia, Lymphocytic, Chronic, B-Cell -- blood
- Leukocytes, Mononuclear
- Male
- Middle Aged
- Nitro Compounds -- chemistry
- Primary Cell Culture
- Prognosis
- Purines -- pharmacology
- Quinazolinones -- pharmacology
- Structure-Activity Relationship
- Styrenes -- chemistry
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Publication Type: Journal Article
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