Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis. [electronic resource]
Producer: 20200203Description: 1525-1539 p. digitalISSN:- 1879-260X
- Animals
- Arylalkylamine N-Acetyltransferase -- genetics
- Bile Ducts, Intrahepatic -- metabolism
- CLOCK Proteins -- genetics
- Cell Line
- Cell Proliferation -- radiation effects
- Cholestasis -- genetics
- Epithelial Cells -- metabolism
- Gene Expression Regulation
- Hepatic Stellate Cells -- metabolism
- Humans
- Kupffer Cells -- metabolism
- Light
- Liver -- metabolism
- Liver Cirrhosis -- genetics
- Male
- Melatonin -- biosynthesis
- MicroRNAs -- genetics
- Pineal Gland -- metabolism
- Pinealectomy -- methods
- Primary Cell Culture
- Rats
- Rats, Inbred F344
- Signal Transduction
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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