An Ig Transmembrane Domain Motif Improves the Function of TCRs Transduced in Human T Cells: Implications for Immunotherapy. [electronic resource]
Producer: 20200529Description: 97-109 p. digitalISSN:- 1537-4513
- Amino Acid Motifs
- Amino Acid Sequence
- Animals
- Cell Line
- Gene Expression
- Genetic Therapy
- Genetic Vectors
- Humans
- Immunotherapy, Adoptive
- Lipid Bilayers -- chemistry
- Mice
- Models, Molecular
- Mutagenesis
- Protein Conformation
- Protein Domains -- genetics
- Protein Interaction Domains and Motifs
- Receptors, Antigen, T-Cell -- chemistry
- Receptors, Antigen, T-Cell, alpha-beta -- chemistry
- Receptors, Chimeric Antigen -- chemistry
- Structure-Activity Relationship
- T-Cell Antigen Receptor Specificity -- immunology
- T-Lymphocytes -- immunology
- Transduction, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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